@article {4447,
	title = {Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model.},
	journal = {Front Neurosci},
	volume = {16},
	year = {2022},
	month = {12/2022},
	pages = {932782},
	abstract = {<p>This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec{\textquoteright}s BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.</p>},
	issn = {1662-4548},
	doi = {10.3389/fnins.2022.932782},
	author = {Schalk, Gerwin and Worrell, Samuel and Mivalt, Filip and Belsten, Alexander and Kim, Inyong and Morris, Jonathan M and Hermes, Dora and Klassen, Bryan T and Staff, Nathan P and Messina, Steven and Kaufmann, Timothy and Rickert, J{\"o}rn and Brunner, Peter and Worrell, Gregory A and Miller, Kai J}
}
