@article {4341, title = {Automated intraoperative central sulcus localization and somatotopic mapping using median nerve stimulation.}, journal = {J Neural Eng}, year = {2022}, month = {07/2022}, abstract = {

OBJECTIVE: Accurate identification of functional cortical regions is essential in neurological resection. The central sulcus (CS) is an important landmark that delineates functional cortical regions. Median nerve stimulation (MNS) is a standard procedure to identify the position of the CS intraoperatively. In this paper, we introduce an automated procedure that uses MNS to rapidly localize the CS and create functional somatotopic maps.

APPROACH: We recorded electrocorticographic signals from 13 patients who underwent MNS in the course of an awake craniotomy. We analyzed these signals to develop an automated procedure that determines the location of the CS and that also produces functional somatotopic maps.

MAIN RESULTS: The comparison between our automated method and visual inspection performed by the neurosurgeon shows that our procedure has a high sensitivity (89\%) in identifying the CS. Further, we found substantial concordance between the functional somatotopic maps generated by our method and passive functional mapping (92\% sensitivity).

SIGNIFICANCE: Our automated MNS-based method can rapidly localize the CS and create functional somatotopic maps without imposing additional burden on the clinical procedure. With additional development and validation, our method may lead to a diagnostic tool that guides neurosurgeon and reduces postoperative morbidity in patients undergoing resective brain surgery.

}, issn = {1741-2552}, doi = {10.1088/1741-2552/ac7dfd}, author = {Xie, Tao and Wu, Zehan and Schalk, Gerwin and Tong, Yusheng and Vato, Alessandro and Raviv, Nataly and Guo, Qinglong and Ye, Huanpeng and Sheng, Xinjun and Zhu, Xiangyang and Peter Brunner and Chen, Liang} } @article {4360, title = {Neural oscillations during motor imagery of complex gait: an HdEEG study.}, journal = {Sci Rep}, volume = {12}, year = {2022}, month = {03/2022}, pages = {4314}, abstract = {

The aim of this study was to investigate differences between usual and complex gait motor imagery (MI) task in healthy subjects using high-density electroencephalography (hdEEG) with a MI protocol. We characterized the spatial distribution of α- and β-bands oscillations extracted from hdEEG signals recorded during MI of usual walking (UW) and walking by avoiding an obstacle (Dual-Task, DT). We applied a source localization algorithm to brain regions selected from a large cortical-subcortical network, and then we analyzed α and β bands Event-Related Desynchronizations (ERDs). Nineteen healthy subjects visually imagined walking on a path with (DT) and without (UW) obstacles. Results showed in both gait MI tasks, α- and β-band ERDs in a large cortical-subcortical network encompassing mostly frontal and parietal regions. In most of the regions, we found α- and β-band ERDs in the DT compared with the UW condition. Finally, in the β band, significant correlations emerged between ERDs and scores in imagery ability tests. Overall we detected MI gait-related α- and β-band oscillations in cortical and subcortical areas and significant differences between UW and DT MI conditions. A better understanding of gait neural correlates may lead to a better knowledge of pathophysiology of gait disturbances in neurological diseases.

}, keywords = {Brain, Electroencephalography, Gait, Humans, Imagery, Psychotherapy, Imagination, Walking}, issn = {2045-2322}, doi = {10.1038/s41598-022-07511-x}, author = {Putzolu, Martina and Samogin, Jessica and Cosentino, Carola and Mezzarobba, Susanna and Bonassi, Gaia and Lagravinese, Giovanna and Vato, Alessandro and Mantini, Dante and Avanzino, Laura and Pelosin, Elisa} }