<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Murguialday, A Ramos</style></author><author><style face="normal" font="default" size="100%">Jeremy Jeremy Hill</style></author><author><style face="normal" font="default" size="100%">Bensch, M</style></author><author><style face="normal" font="default" size="100%">Martens, S M M</style></author><author><style face="normal" font="default" size="100%">S Halder</style></author><author><style face="normal" font="default" size="100%">Nijboer, F</style></author><author><style face="normal" font="default" size="100%">Schoelkopf, Bernhard</style></author><author><style face="normal" font="default" size="100%">Niels Birbaumer</style></author><author><style face="normal" font="default" size="100%">Gharabaghi, A</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Transition from the locked in to the completely locked-in state: a physiological analysis.</style></title><secondary-title><style face="normal" font="default" size="100%">Clin Neurophysiol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Clin Neurophysiol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Amyotrophic Lateral Sclerosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Area Under Curve</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain</style></keyword><keyword><style  face="normal" font="default" size="100%">Communication Aids for Disabled</style></keyword><keyword><style  face="normal" font="default" size="100%">Disease Progression</style></keyword><keyword><style  face="normal" font="default" size="100%">Electroencephalography</style></keyword><keyword><style  face="normal" font="default" size="100%">Electromyography</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Signal Processing, Computer-Assisted</style></keyword><keyword><style  face="normal" font="default" size="100%">User-Computer Interface</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">06/2011</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/20888292</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">122</style></volume><pages><style face="normal" font="default" size="100%">925-33</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;h4 style=&quot;font-size: 13px; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; font-family: arial, helvetica, clean, sans-serif; line-height: 17px;&quot;&gt;OBJECTIVE:&amp;nbsp;&lt;/h4&gt;
&lt;p style=&quot;margin: 0px 0px 0.5em; font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;To clarify the physiological and behavioral boundaries between locked-in (LIS) and the completely locked-in state (CLIS) (no voluntary eye movements, no communication possible) through electrophysiological data and to secure&amp;nbsp;&lt;span class=&quot;highlight&quot;&gt;brain-computer-interface&lt;/span&gt;&amp;nbsp;(&lt;span class=&quot;highlight&quot;&gt;BCI&lt;/span&gt;) communication.&lt;/p&gt;
&lt;h4 style=&quot;font-size: 13px; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; font-family: arial, helvetica, clean, sans-serif; line-height: 17px;&quot;&gt;METHODS:&amp;nbsp;&lt;/h4&gt;
&lt;p style=&quot;margin: 0px 0px 0.5em; font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;Electromyography from facial muscles, external anal sphincter (EAS), electrooculography and electrocorticographic data during different psychophysiological tests were acquired to define electrophysiological differences in an amyotrophic lateral sclerosis (ALS) patient with an intracranially implanted grid of 112 electrodes for nine months while the patient passed from the LIS to the CLIS.&lt;/p&gt;
&lt;h4 style=&quot;font-size: 13px; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; font-family: arial, helvetica, clean, sans-serif; line-height: 17px;&quot;&gt;RESULTS:&amp;nbsp;&lt;/h4&gt;
&lt;p style=&quot;margin: 0px 0px 0.5em; font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;At the very end of the LIS there was no facial muscle activity, nor external anal sphincter but eye control. Eye movements were slow and lasted for short periods only. During CLIS event related&amp;nbsp;&lt;span class=&quot;highlight&quot;&gt;brain&lt;/span&gt;potentials (ERP) to passive limb movements and auditory stimuli were recorded, vibrotactile stimulation of different body parts resulted in no ERP response.&lt;/p&gt;
&lt;h4 style=&quot;font-size: 13px; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; font-family: arial, helvetica, clean, sans-serif; line-height: 17px;&quot;&gt;CONCLUSIONS:&amp;nbsp;&lt;/h4&gt;
&lt;p style=&quot;margin: 0px 0px 0.5em; font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;The results presented contradict the commonly accepted assumption that the EAS is the last remaining muscle under voluntary control and demonstrate complete loss of eye movements in CLIS. The eye muscle was shown to be the last muscle group under voluntary control. The findings suggest ALS as a multisystem disorder, even affecting afferent sensory pathways.&lt;/p&gt;
&lt;h4 style=&quot;font-size: 13px; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left; font-family: arial, helvetica, clean, sans-serif; line-height: 17px;&quot;&gt;SIGNIFICANCE:&amp;nbsp;&lt;/h4&gt;
&lt;p style=&quot;margin: 0px 0px 0.5em; font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;Auditory and proprioceptive&amp;nbsp;&lt;span class=&quot;highlight&quot;&gt;brain-computer-interface&lt;/span&gt;&amp;nbsp;(&lt;span class=&quot;highlight&quot;&gt;BCI&lt;/span&gt;) systems are the only remaining communication channels in CLIS.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Haselager, Pim</style></author><author><style face="normal" font="default" size="100%">Vlek, Rutger</style></author><author><style face="normal" font="default" size="100%">Jeremy Jeremy Hill</style></author><author><style face="normal" font="default" size="100%">Nijboer, F</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A note on ethical aspects of BCI.</style></title><secondary-title><style face="normal" font="default" size="100%">Neural Netw</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Neural Netw</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioethics</style></keyword><keyword><style  face="normal" font="default" size="100%">Brain</style></keyword><keyword><style  face="normal" font="default" size="100%">Communication</style></keyword><keyword><style  face="normal" font="default" size="100%">Communications Media</style></keyword><keyword><style  face="normal" font="default" size="100%">Cooperative Behavior</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Informed Consent</style></keyword><keyword><style  face="normal" font="default" size="100%">Professional-Patient Relations</style></keyword><keyword><style  face="normal" font="default" size="100%">Quadriplegia</style></keyword><keyword><style  face="normal" font="default" size="100%">User-Computer Interface</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">11/2009 </style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/19616405</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">22</style></volume><pages><style face="normal" font="default" size="100%">1352-7</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;This paper focuses on ethical aspects of BCI, as a research and a clinical tool, that are challenging for practitioners currently working in the field. Specifically, the difficulties involved in acquiring informed consent from locked-in patients are investigated, in combination with an analysis of the shared moral responsibility in BCI teams, and the complications encountered in establishing effective communication with media.&lt;/span&gt;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">9</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>5</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hinterberger, T.</style></author><author><style face="normal" font="default" size="100%">Nijboer, F</style></author><author><style face="normal" font="default" size="100%">Kübler, A.</style></author><author><style face="normal" font="default" size="100%">Matuz, T.</style></author><author><style face="normal" font="default" size="100%">Adrian Furdea</style></author><author><style face="normal" font="default" size="100%">Mochty, Ursula</style></author><author><style face="normal" font="default" size="100%">Jordan, M.</style></author><author><style face="normal" font="default" size="100%">Lal, T.N</style></author><author><style face="normal" font="default" size="100%">Jeremy Jeremy Hill</style></author><author><style face="normal" font="default" size="100%">Mellinger, Jürgen</style></author><author><style face="normal" font="default" size="100%">Bensch, M</style></author><author><style face="normal" font="default" size="100%">Tangermann, Michael</style></author><author><style face="normal" font="default" size="100%">Widmann, G.</style></author><author><style face="normal" font="default" size="100%">Elger, Christian</style></author><author><style face="normal" font="default" size="100%">Rosenstiel, W.</style></author><author><style face="normal" font="default" size="100%">Schölkopf, B</style></author><author><style face="normal" font="default" size="100%">Niels Birbaumer</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Brain Computer Interfaces for Communication in Paralysis: a Clinical-Experimental Approach.</style></title></titles><keywords><keyword><style  face="normal" font="default" size="100%">brain-computer interfaces</style></keyword><keyword><style  face="normal" font="default" size="100%">EEG</style></keyword><keyword><style  face="normal" font="default" size="100%">experiment</style></keyword><keyword><style  face="normal" font="default" size="100%">Medical sciences Medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">paralyzed patients</style></keyword><keyword><style  face="normal" font="default" size="100%">slow cortical potentials</style></keyword><keyword><style  face="normal" font="default" size="100%">Thought-Translation Device</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2007</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://psydok.sulb.uni-saarland.de/volltexte/2008/2154/</style></url></web-urls></urls><publisher><style face="normal" font="default" size="100%">Virtual Library of Psychology at Saarland University and State Library, GERMANY, PsyDok [http://psydok.sulb.uni-saarland.de/phpoai/oai2.php] (Germany)</style></publisher><isbn><style face="normal" font="default" size="100%">9780262256049</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span style=&quot;color: #333333; font-family: sans-serif; font-size: 15px; line-height: 24px;&quot;&gt;An overview of different approaches to brain-computer interfaces (BCIs) developed in our laboratory is given. An important clinical application of BCIs is to enable communication or environmental control in severely paralyzed patients. The BCI “Thought-Translation Device (TTD)” allows verbal communication through the voluntary self-regulation of brain signals (e.g., slow cortical potentials (SCPs)), which is achieved by operant feedback training. Humans' ability to self-regulate their SCPs is used to move a cursor toward a target that contains a selectable letter set. Two different approaches were followed to developWeb browsers that could be controlled with binary brain responses. Implementing more powerful classification methods including different signal parameters such as oscillatory features improved our BCI considerably. It was also tested on signals with implanted electrodes. Most BCIs provide the user with a visual feedback interface. Visually impaired patients require an auditory feedback mode. A procedure using auditory (sonified) feedback of multiple EEG parameters was evaluated. Properties of the auditory systems are reported and the results of two experiments with auditory feedback are presented. Clinical data of eight ALS patients demonstrated that all patients were able to acquire efficient brain control of one of the three available BCI systems (SCP, µ-rhythm, and P300), most of them used the SCP-BCI. A controlled comparison of the three systems in a group of ALS patients, however, showed that P300-BCI and the µ-BCI are faster and more easily acquired than SCP-BCI, at least in patients with some rudimentary motor control left. Six patients who started BCI training after entering the completely locked-in state did not achieve reliable communication skills with any BCI system. One completely locked-in patient was able t o communicate shortly with a ph-meter, but lost control afterward.&lt;/span&gt;&lt;/p&gt;</style></abstract></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jeremy Jeremy Hill</style></author><author><style face="normal" font="default" size="100%">Lal, T.N</style></author><author><style face="normal" font="default" size="100%">Schröder, Michael</style></author><author><style face="normal" font="default" size="100%">Hinterberger, T.</style></author><author><style face="normal" font="default" size="100%">Wilhelm, Barbara</style></author><author><style face="normal" font="default" size="100%">Nijboer, F</style></author><author><style face="normal" font="default" size="100%">Mochty, Ursula</style></author><author><style face="normal" font="default" size="100%">Widman, Guido</style></author><author><style face="normal" font="default" size="100%">Elger, Christian</style></author><author><style face="normal" font="default" size="100%">Schölkopf, B</style></author><author><style face="normal" font="default" size="100%">Kübler, A.</style></author><author><style face="normal" font="default" size="100%">Niels Birbaumer</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Classifying EEG and ECoG signals without subject training for fast BCI implementation: comparison of nonparalyzed and completely paralyzed subjects.</style></title><secondary-title><style face="normal" font="default" size="100%">IEEE Trans Neural Syst Rehabil Eng</style></secondary-title><alt-title><style face="normal" font="default" size="100%">IEEE Trans Neural Syst Rehabil Eng</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Algorithms</style></keyword><keyword><style  face="normal" font="default" size="100%">Artificial Intelligence</style></keyword><keyword><style  face="normal" font="default" size="100%">Cluster Analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Computer User Training</style></keyword><keyword><style  face="normal" font="default" size="100%">Electroencephalography</style></keyword><keyword><style  face="normal" font="default" size="100%">Evoked Potentials</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Imagination</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Paralysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Pattern Recognition, Automated</style></keyword><keyword><style  face="normal" font="default" size="100%">User-Computer Interface</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2006</style></year><pub-dates><date><style  face="normal" font="default" size="100%">06/2006</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/16792289</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">183-6</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;We summarize results from a series of related studies that aim to develop a motor-imagery-&lt;/span&gt;&lt;span class=&quot;highlight&quot; style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;based&lt;/span&gt;&lt;span style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;span class=&quot;highlight&quot; style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;brain-computer interface&lt;/span&gt;&lt;span style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;&amp;nbsp;using a single recording session of electroencephalogram (EEG) or electrocorticogram (ECoG) signals for each subject. We apply the same experimental and analytical methods to 11 nonparalysed subjects (eight EEG, three ECoG), and to five paralyzed subjects (four EEG, one ECoG) who had been unable to communicate for some time. While it was relatively easy to obtain classifiable signals quickly from most of the nonparalyzed subjects, it proved impossible to classify the signals obtained from the paralyzed patients by the same methods. This highlights the fact that though certain BCI paradigms may work well with healthy subjects, this does not necessarily indicate success with the target user group. We outline possible reasons for this failure to transfer.&lt;/span&gt;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kübler, A.</style></author><author><style face="normal" font="default" size="100%">Nijboer, F</style></author><author><style face="normal" font="default" size="100%">Mellinger, Jürgen</style></author><author><style face="normal" font="default" size="100%">Theresa M Vaughan</style></author><author><style face="normal" font="default" size="100%">Pawelzik, H</style></author><author><style face="normal" font="default" size="100%">Gerwin Schalk</style></author><author><style face="normal" font="default" size="100%">Dennis J. McFarland</style></author><author><style face="normal" font="default" size="100%">Niels Birbaumer</style></author><author><style face="normal" font="default" size="100%">Jonathan Wolpaw</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Patients with ALS can use sensorimotor rhythms to operate a brain-computer interface.</style></title><secondary-title><style face="normal" font="default" size="100%">Neurology</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Neurology</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Amyotrophic Lateral Sclerosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Electroencephalography</style></keyword><keyword><style  face="normal" font="default" size="100%">Evoked Potentials, Motor</style></keyword><keyword><style  face="normal" font="default" size="100%">Evoked Potentials, Somatosensory</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Imagination</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Middle Aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Motor Cortex</style></keyword><keyword><style  face="normal" font="default" size="100%">Movement</style></keyword><keyword><style  face="normal" font="default" size="100%">Paralysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Photic Stimulation</style></keyword><keyword><style  face="normal" font="default" size="100%">Prostheses and Implants</style></keyword><keyword><style  face="normal" font="default" size="100%">Somatosensory Cortex</style></keyword><keyword><style  face="normal" font="default" size="100%">Treatment Outcome</style></keyword><keyword><style  face="normal" font="default" size="100%">User-Computer Interface</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2005</style></year><pub-dates><date><style  face="normal" font="default" size="100%">05/2005</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/15911809</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">64</style></volume><pages><style face="normal" font="default" size="100%">1775-7</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;span style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;People with severe motor disabilities can maintain an acceptable quality of life if they can communicate.&amp;nbsp;&lt;/span&gt;&lt;span class=&quot;highlight&quot; style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;Brain-computer interfaces&lt;/span&gt;&lt;span style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;&amp;nbsp;(BCIs), which do not depend on muscle control, can provide communication. Four people severely disabled by ALS learned to operate a BCI with EEG rhythms recorded over sensorimotor cortex. These results suggest that a sensorimotor rhythm-&lt;/span&gt;&lt;span class=&quot;highlight&quot; style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;based&lt;/span&gt;&lt;span style=&quot;font-family: arial, helvetica, clean, sans-serif; font-size: 13px; line-height: 17px;&quot;&gt;&amp;nbsp;BCI could help maintain quality of life for people with ALS.&lt;/span&gt;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">10</style></issue></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mellinger, Jürgen</style></author><author><style face="normal" font="default" size="100%">Nijboer, F</style></author><author><style face="normal" font="default" size="100%">Pawelzik, H</style></author><author><style face="normal" font="default" size="100%">Gerwin Schalk</style></author><author><style face="normal" font="default" size="100%">Dennis J. McFarland</style></author><author><style face="normal" font="default" size="100%">Theresa M Vaughan</style></author><author><style face="normal" font="default" size="100%">Jonathan Wolpaw</style></author><author><style face="normal" font="default" size="100%">Niels Birbaumer</style></author><author><style face="normal" font="default" size="100%">Kuebler, A.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">P300 for communication: Evidence from patients with amyotrophic lateral sclerosis (ALS).</style></title><secondary-title><style face="normal" font="default" size="100%">Biomedizinische Technik</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2004</style></year></dates><language><style face="normal" font="default" size="100%">eng</style></language></record></records></xml>