| Title | Ablation of the inferior olive prevents H-reflex down-conditioning in rats. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Chen, XY, Wang, Y, Chen, Y, Chen, L, Wolpaw, J |
| Journal | Journal of neurophysiology |
| Volume | 115 |
| Pagination | 1630–1636 |
| Date Published | Mar |
| ISSN | 1522-1598 |
| Keywords | Spinal Cord |
| Abstract | We evaluated the role of the inferior olive (IO) in acquisition of the spinal cord plasticity that underlies H-reflex down-conditioning, a simple motor skill. The IO was chemically ablated before a 50-day exposure to an operant conditioning protocol that rewarded a smaller soleus H-reflex. In normal rats, down-conditioning succeeds (i.e., H-reflex size decreases at least 20%) in 80% of animals. Down-conditioning failed in every IO-ablated rat (P |
| URL | http://www.ncbi.nlm.nih.gov/pubmed/26792888 |
| DOI | 10.1152/jn.01069.2015 |
