Yi Chen, PhD

TR&D 2 Co-Leader

National Center for Adaptive Neurotechnologies
Stratton VA Medical Center
113 Holland Avenue, Albany, NY 12208

I have a broad background in neuroscience, with specific training and expertise in electrophysiological, behavioral, and functional studies of neuronal plasticity and repair in the spinal cord. I have been involved in projects to explore CNS plasticity induced by reflex conditioning and its potential usefulness in treatment of spinal cord injuries since 2002 when I became a graduate student at the Ohio State University and at the Wadsworth Center, I have continued these important studies as a postdoctoral fellow and now as a research scientist. I have focused particularly on exploring whether conditioning-induced plasticity affects locomotor function, and whether it can improve locomotion after spinal cord injury. In the past 11 years, I have mastered many important surgical techniques, including implantation of chronic stimulation and recording electrodes, targeted spinal cord pathway transections, targeted spinal cord contusion injuries, targeted brain structure ablations, and peripheral nerve injury and repair. I am able to skillfully operate our lab’s unique computer-controlled automatic long-term data collection system, including setting up the training parameters for animals and daily monitoring and adjusting of the data acquisition system. In addition, working with Drs. Wolpaw and XY Chen, I have developed and validated many specialized techniques for evaluating the effects of changes in existing motor skills and in functional recovery, including treadmill walking gait assessment and analysis, locomotor EMG activity assessment and analysis, video and computerized kinematic analysis, locomotor electrocorticographic (ECoG) activity assessment and analysis, and a number of other behavioral measures.

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