Title | A motor association area in the depths of the central sulcus. |
Publication Type | Journal Article |
Year of Publication | 2023 |
Authors | Jensen, MA, Huang, H, Valencia, GOjeda, Klassen, BT, van den Boom, MA, Kaufmann, TJ, Schalk, G, Brunner, P, Worrell, GA, Hermes, D, Miller, KJ |
Journal | Nat Neurosci |
Volume | 26 |
Issue | 7 |
Pagination | 1165-1169 |
Date Published | 07/2023 |
ISSN | 1546-1726 |
Keywords | Brain Mapping, Motor Cortex, Movement |
Abstract | Cells in the precentral gyrus directly send signals to the periphery to generate movement and are principally organized as a topological map of the body. We find that movement-induced electrophysiological responses from depth electrodes extend this map three-dimensionally throughout the gyrus. Unexpectedly, this organization is interrupted by a previously undescribed motor association area in the depths of the midlateral aspect of the central sulcus. This 'Rolandic motor association' (RMA) area is active during movements of different body parts from both sides of the body and may be important for coordinating complex behaviors. |
DOI | 10.1038/s41593-023-01346-z |
Alternate Journal | Nat Neurosci |
PubMed ID | 37202552 |
PubMed Central ID | PMC10322697 |
Grant List | KL2 TR002379 / TR / NCATS NIH HHS / United States U24 NS109103 / NS / NINDS NIH HHS / United States U01 NS108916 / NS / NINDS NIH HHS / United States U01 NS128612 / NS / NINDS NIH HHS / United States R01 EB026439 / EB / NIBIB NIH HHS / United States P41 EB018783 / EB / NIBIB NIH HHS / United States |